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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCQ
All Species:
52.42
Human Site:
Y556
Identified Species:
76.89
UniProt:
Q04759
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04759
NP_006248.1
706
81865
Y556
E
I
L
L
G
Q
K
Y
N
H
S
V
D
W
W
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
Y556
E
I
L
L
G
Q
K
Y
N
H
S
V
D
W
W
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
Y989
E
I
L
Q
G
L
K
Y
T
F
S
V
D
W
W
Dog
Lupus familis
XP_849292
706
81555
Y556
E
I
L
L
G
Q
K
Y
N
H
S
V
D
W
W
Cat
Felis silvestris
Mouse
Mus musculus
Q02111
707
81555
Y556
E
I
L
L
G
Q
K
Y
N
H
S
V
D
W
W
Rat
Rattus norvegicus
Q9WTQ0
707
81732
Y556
E
I
L
L
G
Q
K
Y
N
H
S
V
D
W
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
Y558
E
I
L
L
G
Q
K
Y
N
T
S
V
D
W
W
Chicken
Gallus gallus
NP_001006133
699
80179
Y548
E
I
L
Q
G
L
K
Y
T
F
S
V
D
W
W
Frog
Xenopus laevis
Q7LZQ8
671
76506
Y515
G
I
I
R
Y
Q
P
Y
A
K
S
V
D
W
W
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
Y515
E
I
I
A
Y
Q
P
Y
G
K
S
V
D
W
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
Y479
E
I
L
K
E
Q
E
Y
G
A
S
V
D
W
W
Honey Bee
Apis mellifera
XP_394743
624
71014
Y478
E
I
I
K
G
L
K
Y
N
Q
A
V
D
W
W
Nematode Worm
Caenorhab. elegans
P34722
704
80280
Y552
E
I
I
K
G
Q
L
Y
N
E
A
V
D
F
W
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
H478
C
I
L
H
D
A
P
H
F
P
R
W
L
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
Y1001
E
I
L
K
E
Q
E
Y
T
K
A
V
D
W
W
Red Bread Mold
Neurospora crassa
P87253
1142
127954
Y994
E
I
L
L
D
K
K
Y
G
R
A
V
D
W
W
Conservation
Percent
Protein Identity:
100
99.7
33.6
96.7
N.A.
94.7
94
N.A.
86.1
63.3
33.9
34.1
N.A.
42.9
43.2
47.1
47.8
Protein Similarity:
100
99.7
45.1
98.3
N.A.
97.5
96.8
N.A.
92.9
77.1
48.2
49.2
N.A.
58.7
58.9
64.1
62
P-Site Identity:
100
100
73.3
100
N.A.
100
100
N.A.
93.3
73.3
53.3
60
N.A.
66.6
66.6
60
13.3
P-Site Similarity:
100
100
73.3
100
N.A.
100
100
N.A.
93.3
73.3
60
66.6
N.A.
73.3
80
80
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.2
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.3
40.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
7
0
0
7
7
25
0
0
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
13
0
0
0
0
0
0
0
94
0
0
% D
% Glu:
88
0
0
0
13
0
13
0
0
7
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
7
13
0
0
0
7
0
% F
% Gly:
7
0
0
0
63
0
0
0
19
0
0
0
0
0
0
% G
% His:
0
0
0
7
0
0
0
7
0
32
0
0
0
0
0
% H
% Ile:
0
100
25
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
25
0
7
63
0
0
19
0
0
0
0
7
% K
% Leu:
0
0
75
44
0
19
7
0
0
0
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
19
0
0
7
0
0
0
0
0
% P
% Gln:
0
0
0
13
0
69
0
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
0
7
0
0
0
0
0
7
7
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
69
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
19
7
0
0
0
7
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
94
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
88
94
% W
% Tyr:
0
0
0
0
13
0
0
94
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _